Precise detection of a murine germline mutation of the Notch3 gene associated with kyphosis and developmental disorders

OBJECTIVE: Humpback (hpbk) mice harbor a pathogenic mutation in the Notch3 gene and can serve as a beneficial animal model for investigating human myopathy, kyphosis, and developmental disorders, including lateral meningocele syndrome. Detection of the point mutation in hpbk mice is important for ma...

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Detalles Bibliográficos
Autores principales: Torres, Haydee M., Rodezno-Antunes, Tania, VanCleave, Ashley, Cao, Yuxia, Callahan, Dakota L., Westendorf, Jennifer J., Tao, Jianning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: A periodical of the Network for the Veterinarians of Bangladesh (BDvetNET) 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8043348/
https://www.ncbi.nlm.nih.gov/pubmed/33860007
http://dx.doi.org/10.5455/javar.2021.h479

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8043348/
https://www.ncbi.nlm.nih.gov/pubmed/33860007
http://dx.doi.org/10.5455/javar.2021.h479

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