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Precise detection of a murine germline mutation of the Notch3 gene associated with kyphosis and developmental disorders
OBJECTIVE: Humpback (hpbk) mice harbor a pathogenic mutation in the Notch3 gene and can serve as a beneficial animal model for investigating human myopathy, kyphosis, and developmental disorders, including lateral meningocele syndrome. Detection of the point mutation in hpbk mice is important for ma...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
A periodical of the Network for the Veterinarians of Bangladesh (BDvetNET)
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8043348/ https://www.ncbi.nlm.nih.gov/pubmed/33860007 http://dx.doi.org/10.5455/javar.2021.h479 |