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Stress and odorant receptor feedback during a critical period after hatching regulates olfactory sensory neuron differentiation in Drosophila

Here, we reveal that the regulation of Drosophila odorant receptor (OR) expression during the pupal stage is permissive and imprecise. We found that directly after hatching an OR feedback mechanism both directs and refines OR expression. We demonstrate that, as in mice, dLsd1 and Su(var)3-9 balance...

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Detalles Bibliográficos
Autores principales: Jafari, Shadi, Henriksson, Johan, Yan, Hua, Alenius, Mattias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8043390/
https://www.ncbi.nlm.nih.gov/pubmed/33793547
http://dx.doi.org/10.1371/journal.pbio.3001101