mRNA vaccination compared to infection elicits an IgG-predominant response with greater SARS-CoV-2 specificity and similar decrease in variant spike recognition

During the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic, new vaccine strategies including lipid nanoparticle delivery of antigen encoding RNA have been deployed globally. The BioNTech/Pfizer mRNA vaccine BNT162b2 encoding SARS-CoV-2 spike protein shows 95% efficacy in preven...

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Detalles Bibliográficos
Autores principales: Röltgen, Katharina, Nielsen, Sandra C. A., Arunachalam, Prabhu S., Yang, Fan, Hoh, Ramona A., Wirz, Oliver F., Lee, Alexandra S., Gao, Fei, Mallajosyula, Vamsee, Li, Chunfeng, Haraguchi, Emily, Shoura, Massa J., Wilbur, James L., Wohlstadter, Jacob N., Davis, Mark M., Pinsky, Benjamin A., Sigal, George B., Pulendran, Bali, Nadeau, Kari C., Boyd, Scott D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8043478/
https://www.ncbi.nlm.nih.gov/pubmed/33851181
http://dx.doi.org/10.1101/2021.04.05.21254952

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8043478/
https://www.ncbi.nlm.nih.gov/pubmed/33851181
http://dx.doi.org/10.1101/2021.04.05.21254952

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