Pharmacokinetics and Safety of Zidovudine, Lamivudine, and Lopinavir/Ritonavir in HIV-infected Children With Severe Acute Malnutrition in Sub-Saharan Africa: IMPAACT Protocol P1092

Severe acute malnutrition (SAM) may alter the pharmacokinetics (PK), efficacy, and safety of antiretroviral therapy. The phase IV study, IMPAACT P1092, compared PK, safety, and tolerability of zidovudine (ZDV), lamivudine (3TC), and lopinavir/ritonavir (LPV/r) in children with and without SAM. MATER...

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Detalles Bibliográficos
Autores principales: Owor, Maxensia, Tierney, Camlin, Ziemba, Lauren, Browning, Renee, Moye, John, Graham, Bobbie, Reding, Christina, Costello, Diane, Norman, Jennifer, Wiesner, Lubbe, Hughes, Emma, Whalen, Meghan E., Purdue, Lynette, Mmbaga, Blandina Theophil, Kamthunzi, Portia, Kawalazira, Rachel, Nathoo, Kusum, Bradford, Sarah, Coletti, Anne, Aweeka, Francesca., Musoke, Philippa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2021
Materias:
HIV Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8043511/
https://www.ncbi.nlm.nih.gov/pubmed/33464021
http://dx.doi.org/10.1097/INF.0000000000003055

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8043511/
https://www.ncbi.nlm.nih.gov/pubmed/33464021
http://dx.doi.org/10.1097/INF.0000000000003055

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