A genetic screen identifies new steps in oocyte maturation that enhance proteostasis in the immortal germ lineage

Somatic cells age and die, but the germ-cell lineage is immortal. In Caenorhabditis elegans, germline immortality involves proteostasis renewal at the beginning of each new generation, when oocyte maturation signals from sperm trigger the clearance of carbonylated proteins and protein aggregates. He...

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Detalles Bibliográficos
Autores principales: Samaddar, Madhuja, Goudeau, Jérôme, Sanchez, Melissa, Hall, David H, Bohnert, K Adam, Ingaramo, Maria, Kenyon, Cynthia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8043744/
https://www.ncbi.nlm.nih.gov/pubmed/33848238
http://dx.doi.org/10.7554/eLife.62653

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8043744/
https://www.ncbi.nlm.nih.gov/pubmed/33848238
http://dx.doi.org/10.7554/eLife.62653

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