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Converting endogenous genes of the malaria mosquito into simple non-autonomous gene drives for population replacement

Gene drives for mosquito population replacement are promising tools for malaria control. However, there is currently no clear pathway for safely testing such tools in endemic countries. The lack of well-characterized promoters for infection-relevant tissues and regulatory hurdles are further obstacl...

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Detalles Bibliográficos
Autores principales: Hoermann, Astrid, Tapanelli, Sofia, Capriotti, Paolo, Del Corsano, Giuseppe, Masters, Ellen KG, Habtewold, Tibebu, Christophides, George K, Windbichler, Nikolai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8043746/
https://www.ncbi.nlm.nih.gov/pubmed/33845943
http://dx.doi.org/10.7554/eLife.58791