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Cryo-EM structure of the yeast TREX complex and coordination with the SR-like protein Gbp2

The evolutionarily conserved TRanscript-EXport (TREX) complex plays central roles during mRNP (messenger ribonucleoprotein) maturation and export from the nucleus to the cytoplasm. In yeast, TREX is composed of the THO sub-complex (Tho2, Hpr1, Tex1, Mft1, and Thp2), the DEAD box ATPase Sub2, and Yra...

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Detalles Bibliográficos
Autores principales: Xie, Yihu, Clarke, Bradley P, Kim, Yong Joon, Ivey, Austin L, Hill, Pate S, Shi, Yi, Ren, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8043747/
https://www.ncbi.nlm.nih.gov/pubmed/33787496
http://dx.doi.org/10.7554/eLife.65699