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Mapping the functional landscape of the receptor binding domain of T7 bacteriophage by deep mutational scanning
The interaction between a bacteriophage and its host is mediated by the phage's receptor binding protein (RBP). Despite its fundamental role in governing phage activity and host range, molecular rules of RBP function remain a mystery. Here, we systematically dissect the functional role of every...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
eLife Sciences Publications, Ltd
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8043750/ https://www.ncbi.nlm.nih.gov/pubmed/33687327 http://dx.doi.org/10.7554/eLife.63775 |