Cardiovascular disease risk factors induce mesenchymal features and senescence in mouse cardiac endothelial cells

Aging, obesity, hypertension, and physical inactivity are major risk factors for endothelial dysfunction and cardiovascular disease (CVD). We applied fluorescence-activated cell sorting (FACS), RNA sequencing, and bioinformatic methods to investigate the common effects of CVD risk factors in mouse c...

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Detalles Bibliográficos
Autores principales: Hemanthakumar, Karthik Amudhala, Fang, Shentong, Anisimov, Andrey, Mäyränpää, Mikko I, Mervaala, Eero, Kivelä, Riikka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Chromosomes and Gene Expression
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8043751/
https://www.ncbi.nlm.nih.gov/pubmed/33661096
http://dx.doi.org/10.7554/eLife.62678

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8043751/
https://www.ncbi.nlm.nih.gov/pubmed/33661096
http://dx.doi.org/10.7554/eLife.62678

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