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Plasma p-tau231: a new biomarker for incipient Alzheimer’s disease pathology

The quantification of phosphorylated tau in biofluids, either cerebrospinal fluid (CSF) or plasma, has shown great promise in detecting Alzheimer’s disease (AD) pathophysiology. Tau phosphorylated at threonine 231 (p-tau231) is one such biomarker in CSF but its usefulness as a blood biomarker is cur...

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Detalles Bibliográficos
Autores principales: Ashton, Nicholas J., Pascoal, Tharick A., Karikari, Thomas K., Benedet, Andréa L., Lantero-Rodriguez, Juan, Brinkmalm, Gunnar, Snellman, Anniina, Schöll, Michael, Troakes, Claire, Hye, Abdul, Gauthier, Serge, Vanmechelen, Eugeen, Zetterberg, Henrik, Rosa-Neto, Pedro, Blennow, Kaj
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8043944/
https://www.ncbi.nlm.nih.gov/pubmed/33585983
http://dx.doi.org/10.1007/s00401-021-02275-6