The protein kinase Ire1 impacts pathogenicity of Candida albicans by regulating homeostatic adaptation to endoplasmic reticulum stress

The unfolded protein response (UPR), crucial for the maintenance of endoplasmic reticulum (ER) homeostasis, is tied to the regulation of multiple cellular processes in pathogenic fungi. Here, we show that Candida albicans relies on an ER‐resident protein, inositol‐requiring enzyme 1 (Ire1) for sensi...

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Detalles Bibliográficos
Autores principales: Sircaik, Shabnam, Román, Elvira, Bapat, Priyanka, Lee, Keunsook K., Andes, David R., Gow, Neil A. R., Nobile, Clarissa J., Pla, Jesús, Panwar, Sneh Lata
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8044019/
https://www.ncbi.nlm.nih.gov/pubmed/33403715
http://dx.doi.org/10.1111/cmi.13307

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8044019/
https://www.ncbi.nlm.nih.gov/pubmed/33403715
http://dx.doi.org/10.1111/cmi.13307

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