Low biological fluctuation of mitochondrial CpG and non-CpG methylation at the single-molecule level

Mammalian cytosine DNA methylation (5mC) is associated with the integrity of the genome and the transcriptional status of nuclear DNA. Due to technical limitations, it has been less clear if mitochondrial DNA (mtDNA) is methylated and whether 5mC has a regulatory role in this context. Here, we used...

Descripción completa

Detalles Bibliográficos
Autores principales: Goldsmith, Chloe, Rodríguez-Aguilera, Jesús Rafael, El-Rifai, Ines, Jarretier-Yuste, Adrien, Hervieu, Valérie, Raineteau, Olivier, Saintigny, Pierre, Chagoya de Sánchez, Victoria, Dante, Robert, Ichim, Gabriel, Hernandez-Vargas, Hector
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8044111/
https://www.ncbi.nlm.nih.gov/pubmed/33850190
http://dx.doi.org/10.1038/s41598-021-87457-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8044111/
https://www.ncbi.nlm.nih.gov/pubmed/33850190
http://dx.doi.org/10.1038/s41598-021-87457-8

Ejemplares similares