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GOLM1 restricts colitis and colon tumorigenesis by ensuring Notch signaling equilibrium in intestinal homeostasis

Intestinal epithelium serves as the first barrier against the infections and injuries that mediate colonic inflammation. Colorectal cancer is often accompanied with chronic inflammation. Differed from its well-known oncogenic role in many malignancies, we present here that Golgi membrane protein 1 (...

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Detalles Bibliográficos
Autores principales: Pu, Yang, Song, Ya, Zhang, Mengdi, Long, Caifeng, Li, Jie, Wang, Yanan, Xu, Yinzhe, Pan, Fei, Zhao, Na, Zhang, Xinyu, Xu, Yanan, Cui, Jianxin, Wang, Hongying, Li, Yan, Zhao, Yong, Jin, Di, Zhang, Hongbing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8044123/
https://www.ncbi.nlm.nih.gov/pubmed/33850109
http://dx.doi.org/10.1038/s41392-021-00535-1