Chemotherapy confers a conserved secondary tolerance to EGFR inhibition via AXL-mediated signaling bypass

Drug resistance remains the major culprit of therapy failure in disseminated cancers. Simultaneous resistance to multiple, chemically different drugs feeds this failure resulting in cancer relapse. Here, we investigate co-resistance signatures shared between antimitotic drugs (AMDs) and inhibitors o...

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Detalles Bibliográficos
Autores principales: Aldonza, Mark Borris D., Reyes, Roben D. Delos, Kim, Young Seo, Ku, Jayoung, Barsallo, Ana Melisa, Hong, Ji-Young, Lee, Sang Kook, Ryu, Han Suk, Park, YongKeun, Cho, Je-Yoel, Kim, Yoosik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8044124/
https://www.ncbi.nlm.nih.gov/pubmed/33850249
http://dx.doi.org/10.1038/s41598-021-87599-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8044124/
https://www.ncbi.nlm.nih.gov/pubmed/33850249
http://dx.doi.org/10.1038/s41598-021-87599-9

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