Structural basis of norepinephrine recognition and transport inhibition in neurotransmitter transporters

Norepinephrine is a biogenic amine neurotransmitter that has widespread effects on alertness, arousal and pain sensation. Consequently, blockers of norepinephrine uptake have served as vital tools to treat depression and chronic pain. Here, we employ the Drosophila melanogaster dopamine transporter...

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Detalles Bibliográficos
Autores principales: Pidathala, Shabareesh, Mallela, Aditya Kumar, Joseph, Deepthi, Penmatsa, Aravind
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8044178/
https://www.ncbi.nlm.nih.gov/pubmed/33850134
http://dx.doi.org/10.1038/s41467-021-22385-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8044178/
https://www.ncbi.nlm.nih.gov/pubmed/33850134
http://dx.doi.org/10.1038/s41467-021-22385-9

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