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Characterization of combined linagliptin and Y2R agonist treatment in diet-induced obese mice
Dipeptidyl peptidase IV (DPP-IV) inhibitors improve glycemic control by prolonging the action of glucagon-like peptide-1 (GLP-1). In contrast to GLP-1 analogues, DPP-IV inhibitors are weight-neutral. DPP-IV cleavage of PYY and NPY gives rise to PYY(3-36) and NPY(3-36) which exert potent anorectic ac...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8044192/ https://www.ncbi.nlm.nih.gov/pubmed/33850212 http://dx.doi.org/10.1038/s41598-021-87539-7 |