Integrated transcription factor profiling with transcriptome analysis identifies L1PA2 transposons as global regulatory modulators in a breast cancer model

While transposons are generally silenced in somatic tissues, many transposons escape epigenetic repression in epithelial cancers, become transcriptionally active and contribute to the regulation of human gene expression. We have developed a bioinformatic pipeline for the integrated analysis of trans...

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Detalles Bibliográficos
Autores principales: Jiang, Jiayue-Clara, Rothnagel, Joseph A., Upton, Kyle R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8044218/
https://www.ncbi.nlm.nih.gov/pubmed/33850167
http://dx.doi.org/10.1038/s41598-021-86395-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8044218/
https://www.ncbi.nlm.nih.gov/pubmed/33850167
http://dx.doi.org/10.1038/s41598-021-86395-9

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