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The efficacy of CRISPR-mediated cytosine base editing with the RPS5a promoter in Arabidopsis thaliana

CRISPR/Cas9-mediated genome editing is an important and versatile technology in modern biological research. Recent advancements include base-editing CRISPR tools that enable targeted nucleotide substitutions using a fusion protein comprising a nickase variant of Cas9 and a base deaminase. Improvemen...

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Detalles Bibliográficos
Autores principales: Choi, Minkyung, Yun, Jae-Young, Kim, Jun-Hyuk, Kim, Jin-Soo, Kim, Sang-Tae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8044221/
https://www.ncbi.nlm.nih.gov/pubmed/33850267
http://dx.doi.org/10.1038/s41598-021-87669-y