Inhibition of the NKCC1/NF-κB Signaling Pathway Decreases Inflammation and Improves Brain Edema and Nerve Cell Apoptosis in an SBI Rat Model

Surgical brain injury (SBI) triggers microglia to release numerous inflammatory factors, leading to brain edema and neurological dysfunction. Reducing neuroinflammation and protecting the blood-brain barrier (BBB) are key factors to improve the neurological function and prognosis after SBI. Na(+)-K(...

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Detalles Bibliográficos
Autores principales: Gong, Yating, Wu, Muyao, Shen, Jinchao, Tang, Jiafeng, Li, Jie, Xu, Jianguo, Dang, Baoqi, Chen, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8044300/
https://www.ncbi.nlm.nih.gov/pubmed/33867933
http://dx.doi.org/10.3389/fnmol.2021.641993

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8044300/
https://www.ncbi.nlm.nih.gov/pubmed/33867933
http://dx.doi.org/10.3389/fnmol.2021.641993

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