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Inhibition of the NKCC1/NF-κB Signaling Pathway Decreases Inflammation and Improves Brain Edema and Nerve Cell Apoptosis in an SBI Rat Model
Surgical brain injury (SBI) triggers microglia to release numerous inflammatory factors, leading to brain edema and neurological dysfunction. Reducing neuroinflammation and protecting the blood-brain barrier (BBB) are key factors to improve the neurological function and prognosis after SBI. Na(+)-K(...
Autores principales: | Gong, Yating, Wu, Muyao, Shen, Jinchao, Tang, Jiafeng, Li, Jie, Xu, Jianguo, Dang, Baoqi, Chen, Gang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8044300/ https://www.ncbi.nlm.nih.gov/pubmed/33867933 http://dx.doi.org/10.3389/fnmol.2021.641993 |
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