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Antibodies Against Pseudomonas aeruginosa Alkaline Protease Directly Enhance Disruption of Neutrophil Extracellular Traps Mediated by This Enzyme

Extracellular traps released by neutrophils (NETs) are essential for the clearance of Pseudomonas aeruginosa. Alkaline protease (AprA) secreted by P. aeruginosa negatively correlates with clinical improvement. Moreover, anti-AprA in patients with cystic fibrosis (CF) can help identify patients with...

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Detalles Bibliográficos
Autores principales: Jing, Chendi, Liu, Chenghua, Liu, Yu, Feng, Ruli, Cao, Run, Guan, Zhangchun, Xuan, Bo, Gao, Yaping, Wang, Qi, Yang, Nana, Ma, Yuanfang, Lan, Lefu, Feng, Jiannan, Shen, Beifen, Wang, Hui, Yu, Yanyan, Yang, Guang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8044376/
https://www.ncbi.nlm.nih.gov/pubmed/33868297
http://dx.doi.org/10.3389/fimmu.2021.654649