Adipose-derived stem cells protect motor neurons and reduce glial activation in both in vitro and in vivo models of ALS

Amyotrophic lateral sclerosis (ALS) is a devastating neurodegenerative condition for which new therapeutic options are urgently needed. We injected GFP(+) adipose-derived stem cells (EGFP-ADSCs) directly into the cerebrospinal fluid (CSF) of transgenic SOD1(G93A) mice, a well-characterized model of...

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Detalles Bibliográficos
Autores principales: Ciervo, Yuri, Gatto, Noemi, Allen, Chloe, Grierson, Andrew, Ferraiuolo, Laura, Mead, Richard J., Shaw, Pamela J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8044387/
https://www.ncbi.nlm.nih.gov/pubmed/33869658
http://dx.doi.org/10.1016/j.omtm.2021.03.017

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8044387/
https://www.ncbi.nlm.nih.gov/pubmed/33869658
http://dx.doi.org/10.1016/j.omtm.2021.03.017

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