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Adipose-derived stem cells protect motor neurons and reduce glial activation in both in vitro and in vivo models of ALS

Amyotrophic lateral sclerosis (ALS) is a devastating neurodegenerative condition for which new therapeutic options are urgently needed. We injected GFP(+) adipose-derived stem cells (EGFP-ADSCs) directly into the cerebrospinal fluid (CSF) of transgenic SOD1(G93A) mice, a well-characterized model of...

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Detalles Bibliográficos
Autores principales:	Ciervo, Yuri, Gatto, Noemi, Allen, Chloe, Grierson, Andrew, Ferraiuolo, Laura, Mead, Richard J., Shaw, Pamela J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society of Gene & Cell Therapy 2021
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8044387/ https://www.ncbi.nlm.nih.gov/pubmed/33869658 http://dx.doi.org/10.1016/j.omtm.2021.03.017

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