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Positive Selection in the Light Zone of Germinal Centers

Germinal centers (GCs) are essential sites for the production of high-affinity antibody secreting plasma cells (PCs) and memory-B cells (MBCs), which form the framework of vaccination. Affinity maturation and permissive selection in GCs are key for the production of PCs and MBCs, respectively. For t...

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Detalles Bibliográficos
Autores principales: Nakagawa, Rinako, Calado, Dinis Pedro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8044421/
https://www.ncbi.nlm.nih.gov/pubmed/33868314
http://dx.doi.org/10.3389/fimmu.2021.661678