Cargando…
Positive Selection in the Light Zone of Germinal Centers
Germinal centers (GCs) are essential sites for the production of high-affinity antibody secreting plasma cells (PCs) and memory-B cells (MBCs), which form the framework of vaccination. Affinity maturation and permissive selection in GCs are key for the production of PCs and MBCs, respectively. For t...
Autores principales: | Nakagawa, Rinako, Calado, Dinis Pedro |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8044421/ https://www.ncbi.nlm.nih.gov/pubmed/33868314 http://dx.doi.org/10.3389/fimmu.2021.661678 |
Ejemplares similares
-
Restriction of memory B cell differentiation at the germinal center B cell positive selection stage
por: Toboso-Navasa, Amparo, et al.
Publicado: (2020) -
Permissive selection followed by affinity-based proliferation of GC light zone B cells dictates cell fate and ensures clonal breadth
por: Nakagawa, Rinako, et al.
Publicado: (2021) -
Defects in Germinal Center Selection in SLE
por: Woods, Megan, et al.
Publicado: (2015) -
Committed Human CD23-Negative Light-Zone Germinal Center B Cells Delineate Transcriptional Program Supporting Plasma Cell Differentiation
por: Santamaria, Kathleen, et al.
Publicado: (2021) -
MYC is essential for the formation and maintenance of germinal centers
por: Calado, Dinis Pedro, et al.
Publicado: (2012)