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Hidden suppressive interactions are common in higher-order drug combinations

The rapid increase of multi-drug resistant bacteria has led to a greater emphasis on multi-drug combination treatments. However, some combinations can be suppressive—that is, bacteria grow faster in some drug combinations than when treated with a single drug. Typically, when studying interactions, t...

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Detalles Bibliográficos
Autores principales: Lozano-Huntelman, Natalie Ann, Zhou, April, Tekin, Elif, Cruz-Loya, Mauricio, Østman, Bjørn, Boyd, Sada, Savage, Van M., Yeh, Pamela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8044428/
https://www.ncbi.nlm.nih.gov/pubmed/33870144
http://dx.doi.org/10.1016/j.isci.2021.102355