Cryopreservation of microglia enables single-cell RNA sequencing with minimal effects on disease-related gene expression patterns

Microglia play a key role in brain development, normal homeostasis, and neurodegenerative disorders. Single-cell technologies have led to important findings about microglia, with many animal model studies using single-cell RNA sequencing (scRNA-seq), whereas most human specimen studies using archive...

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Detalles Bibliográficos
Autores principales: Morsey, Brenda, Niu, Meng, Dyavar, Shetty Ravi, Fletcher, Courtney V., Lamberty, Benjamin G., Emanuel, Katy, Fangmeier, Anna, Fox, Howard S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8044433/
https://www.ncbi.nlm.nih.gov/pubmed/33870145
http://dx.doi.org/10.1016/j.isci.2021.102357

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8044433/
https://www.ncbi.nlm.nih.gov/pubmed/33870145
http://dx.doi.org/10.1016/j.isci.2021.102357

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