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Cryopreservation of microglia enables single-cell RNA sequencing with minimal effects on disease-related gene expression patterns
Microglia play a key role in brain development, normal homeostasis, and neurodegenerative disorders. Single-cell technologies have led to important findings about microglia, with many animal model studies using single-cell RNA sequencing (scRNA-seq), whereas most human specimen studies using archive...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8044433/ https://www.ncbi.nlm.nih.gov/pubmed/33870145 http://dx.doi.org/10.1016/j.isci.2021.102357 |