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Increased detection of circulating tumor DNA by short fragment enrichment

BACKGROUND: Circulating cell-free DNA (cfDNA) detection for non-invasive diagnosis requires higher sensitivity and accuracy due to the low circulating tumor DNA (ctDNA) content. Many methods have been developed to improve detection of ctDNA, including ultra-deep sequencing or enrichment of shorter c...

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Detalles Bibliográficos
Autores principales: Liu, Yang, Liu, Yangyang, Wang, Yingying, Li, Lei, Yao, Wenjun, Song, Yingnan, Liu, Bing, Chen, Weihuang, Santarpia, Mariacarmela, Rossi, Elisabetta, Zamarchi, Rita, Wang, Zhe, Wang, Qiming, Cheng, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8044499/
https://www.ncbi.nlm.nih.gov/pubmed/33889525
http://dx.doi.org/10.21037/tlcr-21-180