Computational Drug Repositioning and Experimental Validation of Ivermectin in Treatment of Gastric Cancer

Objective: The aim of the present study was repositioning of ivermectin in treatment of gastric cancer (GC) by computational prediction based on gene expression profiles of human and mouse model of GC and validations with in silico, in vitro and in vivo approaches. Methods: Computational drug reposi...

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Detalles Bibliográficos
Autores principales: Rabben, Hanne-Line, Andersen, Gøran Troseth, Ianevski, Aleksandr, Olsen, Magnus Kringstad, Kainov, Denis, Grønbech, Jon Erik, Wang, Timothy Cragin, Chen, Duan, Zhao, Chun-Mei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8044519/
https://www.ncbi.nlm.nih.gov/pubmed/33867984
http://dx.doi.org/10.3389/fphar.2021.625991

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8044519/
https://www.ncbi.nlm.nih.gov/pubmed/33867984
http://dx.doi.org/10.3389/fphar.2021.625991

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