Proteome Analysis of USP7 Substrates Revealed Its Role in Melanoma Through PI3K/Akt/FOXO and AMPK Pathways

The ubiquitin-specific protease 7 (USP7), as a deubiquitinating enzyme, plays an important role in tumor progression by various mechanisms and serves as a potential therapeutic target. However, the functional role of USP7 in melanoma remains elusive. Here, we found that USP7 is overexpressed in huma...

Descripción completa

Detalles Bibliográficos
Autores principales: Gao, Lanyang, Zhu, Danli, Wang, Qin, Bao, Zheng, Yin, Shigang, Qiang, Huiyan, Wieland, Heinrich, Zhang, Jinyue, Teichmann, Alexander, Jia, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8044529/
https://www.ncbi.nlm.nih.gov/pubmed/33869052
http://dx.doi.org/10.3389/fonc.2021.650165

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8044529/
https://www.ncbi.nlm.nih.gov/pubmed/33869052
http://dx.doi.org/10.3389/fonc.2021.650165

Ejemplares similares