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Proteome Analysis of USP7 Substrates Revealed Its Role in Melanoma Through PI3K/Akt/FOXO and AMPK Pathways

The ubiquitin-specific protease 7 (USP7), as a deubiquitinating enzyme, plays an important role in tumor progression by various mechanisms and serves as a potential therapeutic target. However, the functional role of USP7 in melanoma remains elusive. Here, we found that USP7 is overexpressed in huma...

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Detalles Bibliográficos
Autores principales:	Gao, Lanyang, Zhu, Danli, Wang, Qin, Bao, Zheng, Yin, Shigang, Qiang, Huiyan, Wieland, Heinrich, Zhang, Jinyue, Teichmann, Alexander, Jia, Jing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8044529/ https://www.ncbi.nlm.nih.gov/pubmed/33869052 http://dx.doi.org/10.3389/fonc.2021.650165

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