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Level IV tumor thrombus in non-metastatic renal cell cancer? No, thanks. Level II is better. Lessons learned from a case report
Up to 19% of patients with renal cell carcinoma present with a venous thrombus at diagnosis and 1% have a thrombus extending above the diaphragm. The higher the thrombus level, the more challenging the surgery. Cavoatrial tumor thrombus usually requires circulatory arrest and sometimes cardiopulmona...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8044637/ https://www.ncbi.nlm.nih.gov/pubmed/33868935 http://dx.doi.org/10.1016/j.eucr.2021.101660 |
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author | Galosi, Andrea Benedetto Papaveri, Alessio Castellani, Daniele Agostini, Edoardo Burattini, Luciano Dell’Atti, Lucio |
author_facet | Galosi, Andrea Benedetto Papaveri, Alessio Castellani, Daniele Agostini, Edoardo Burattini, Luciano Dell’Atti, Lucio |
author_sort | Galosi, Andrea Benedetto |
collection | PubMed |
description | Up to 19% of patients with renal cell carcinoma present with a venous thrombus at diagnosis and 1% have a thrombus extending above the diaphragm. The higher the thrombus level, the more challenging the surgery. Cavoatrial tumor thrombus usually requires circulatory arrest and sometimes cardiopulmonary by-pass. We present a case of non-metastatic renal cell carcinoma with a cavoatrial tumor thrombus in a patient who was unfit for cardiac surgery. Eight months of targeted molecular therapy downsized the tumor thrombus to inferior vena cava and allowed us to perform a radical nephrectomy with minimal cavothomy for thrombus resection. |
format | Online Article Text |
id | pubmed-8044637 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-80446372021-04-16 Level IV tumor thrombus in non-metastatic renal cell cancer? No, thanks. Level II is better. Lessons learned from a case report Galosi, Andrea Benedetto Papaveri, Alessio Castellani, Daniele Agostini, Edoardo Burattini, Luciano Dell’Atti, Lucio Urol Case Rep Oncology Up to 19% of patients with renal cell carcinoma present with a venous thrombus at diagnosis and 1% have a thrombus extending above the diaphragm. The higher the thrombus level, the more challenging the surgery. Cavoatrial tumor thrombus usually requires circulatory arrest and sometimes cardiopulmonary by-pass. We present a case of non-metastatic renal cell carcinoma with a cavoatrial tumor thrombus in a patient who was unfit for cardiac surgery. Eight months of targeted molecular therapy downsized the tumor thrombus to inferior vena cava and allowed us to perform a radical nephrectomy with minimal cavothomy for thrombus resection. Elsevier 2021-03-25 /pmc/articles/PMC8044637/ /pubmed/33868935 http://dx.doi.org/10.1016/j.eucr.2021.101660 Text en © 2021 The Authors https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Oncology Galosi, Andrea Benedetto Papaveri, Alessio Castellani, Daniele Agostini, Edoardo Burattini, Luciano Dell’Atti, Lucio Level IV tumor thrombus in non-metastatic renal cell cancer? No, thanks. Level II is better. Lessons learned from a case report |
title | Level IV tumor thrombus in non-metastatic renal cell cancer? No, thanks. Level II is better. Lessons learned from a case report |
title_full | Level IV tumor thrombus in non-metastatic renal cell cancer? No, thanks. Level II is better. Lessons learned from a case report |
title_fullStr | Level IV tumor thrombus in non-metastatic renal cell cancer? No, thanks. Level II is better. Lessons learned from a case report |
title_full_unstemmed | Level IV tumor thrombus in non-metastatic renal cell cancer? No, thanks. Level II is better. Lessons learned from a case report |
title_short | Level IV tumor thrombus in non-metastatic renal cell cancer? No, thanks. Level II is better. Lessons learned from a case report |
title_sort | level iv tumor thrombus in non-metastatic renal cell cancer? no, thanks. level ii is better. lessons learned from a case report |
topic | Oncology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8044637/ https://www.ncbi.nlm.nih.gov/pubmed/33868935 http://dx.doi.org/10.1016/j.eucr.2021.101660 |
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