TRIM26 Induces Ferroptosis to Inhibit Hepatic Stellate Cell Activation and Mitigate Liver Fibrosis Through Mediating SLC7A11 Ubiquitination

Hepatic stellate cells (HSCs) are activated by inflammatory mediators to secrete extracellular matrix for collagen deposition, leading to liver fibrosis. Ferroptosis is iron- and lipid hydroperoxide-dependent programmed cell death, which has recently been targeted for inhibiting liver fibrogenic pro...

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Detalles Bibliográficos
Autores principales: Zhu, Yiming, Zhang, Chihao, Huang, Mingzhe, Lin, Jiayun, Fan, Xiao, Ni, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8044755/
https://www.ncbi.nlm.nih.gov/pubmed/33869196
http://dx.doi.org/10.3389/fcell.2021.644901

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8044755/
https://www.ncbi.nlm.nih.gov/pubmed/33869196
http://dx.doi.org/10.3389/fcell.2021.644901

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