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The Role of Human Centromeric RNA in Chromosome Stability

Chromosome instability is a hallmark of cancer and is caused by inaccurate segregation of chromosomes. One cellular structure used to avoid this fate is the kinetochore, which binds to the centromere on the chromosome. Human centromeres are poorly understood, since sequencing and analyzing repeated...

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Detalles Bibliográficos
Autores principales: Leclerc, Simon, Kitagawa, Katsumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8044762/
https://www.ncbi.nlm.nih.gov/pubmed/33869284
http://dx.doi.org/10.3389/fmolb.2021.642732