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Development of LT-HSC-Reconstituted Non-Irradiated NBSGW Mice for the Study of Human Hematopoiesis In Vivo

Humanized immune system (HIS) mouse models are useful tools for the in vivo investigation of human hematopoiesis. However, the majority of HIS models currently in use are biased towards lymphocyte development and fail to support long-term multilineage leucocytes and erythrocytes. Those that achieve...

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Detalles Bibliográficos
Autores principales: Adigbli, George, Hua, Peng, Uchiyama, Masateru, Roberts, Irene, Hester, Joanna, Watt, Suzanne M., Issa, Fadi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8044770/
https://www.ncbi.nlm.nih.gov/pubmed/33868276
http://dx.doi.org/10.3389/fimmu.2021.642198