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Development of LT-HSC-Reconstituted Non-Irradiated NBSGW Mice for the Study of Human Hematopoiesis In Vivo
Humanized immune system (HIS) mouse models are useful tools for the in vivo investigation of human hematopoiesis. However, the majority of HIS models currently in use are biased towards lymphocyte development and fail to support long-term multilineage leucocytes and erythrocytes. Those that achieve...
Autores principales: | Adigbli, George, Hua, Peng, Uchiyama, Masateru, Roberts, Irene, Hester, Joanna, Watt, Suzanne M., Issa, Fadi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8044770/ https://www.ncbi.nlm.nih.gov/pubmed/33868276 http://dx.doi.org/10.3389/fimmu.2021.642198 |
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