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Human Wharton’s Jelly Stem Cell Secretions Inhibit Human Leukemic Cell Line K562 in vitro by Inducing Cell Cycle Arrest and Apoptosis

Emerging resistance to the tyrosine kinase inhibitors that target the BCR-ABL1 oncoprotein has prompted research for novel therapeutics against chronic myeloid leukemia (CML). Herein, we evaluated the tumor inhibitory properties of the human Wharton’s jelly stem cells (hWJSCs) co-culture (hWJSC-CC)...

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Detalles Bibliográficos
Autores principales: Huwaikem, Muneerah A. H., Kalamegam, Gauthaman, Alrefaei, Ghadeer, Ahmed, Farid, Kadam, Roaa, Qadah, Talal, Sait, Khalid H. W., Pushparaj, Peter N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8044948/
https://www.ncbi.nlm.nih.gov/pubmed/33869169
http://dx.doi.org/10.3389/fcell.2021.614988