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Human Wharton’s Jelly Mesenchymal Stromal Cell-Derived Small Extracellular Vesicles Drive Oligodendroglial Maturation by Restraining MAPK/ERK and Notch Signaling Pathways

Peripartum cerebral hypoxia and ischemia, and intrauterine infection and inflammation, are detrimental for the precursor cells of the myelin-forming oligodendrocytes in the prematurely newborn, potentially leading to white matter injury (WMI) with long-term neurodevelopmental sequelae. Previous data...

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Detalles Bibliográficos
Autores principales: Joerger-Messerli, Marianne S., Thomi, Gierin, Haesler, Valérie, Keller, Irene, Renz, Patricia, Surbek, Daniel V., Schoeberlein, Andreina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8044995/
https://www.ncbi.nlm.nih.gov/pubmed/33869172
http://dx.doi.org/10.3389/fcell.2021.622539