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Human Wharton’s Jelly Mesenchymal Stromal Cell-Derived Small Extracellular Vesicles Drive Oligodendroglial Maturation by Restraining MAPK/ERK and Notch Signaling Pathways
Peripartum cerebral hypoxia and ischemia, and intrauterine infection and inflammation, are detrimental for the precursor cells of the myelin-forming oligodendrocytes in the prematurely newborn, potentially leading to white matter injury (WMI) with long-term neurodevelopmental sequelae. Previous data...
Autores principales: | Joerger-Messerli, Marianne S., Thomi, Gierin, Haesler, Valérie, Keller, Irene, Renz, Patricia, Surbek, Daniel V., Schoeberlein, Andreina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8044995/ https://www.ncbi.nlm.nih.gov/pubmed/33869172 http://dx.doi.org/10.3389/fcell.2021.622539 |
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