Design, synthesis and biological assessment of new 1-benzyl-4-((4-oxoquinazolin-3(4H)-yl)methyl) pyridin-1-ium derivatives (BOPs) as potential dual inhibitors of acetylcholinesterase and butyrylcholinesterase

Alzheimer's disease (AD), is among the most growing neurodegenerative diseases, which is mainly caused by the acetylcholine neurotransmitter loss in the hippocampus and cortex. Emerging of the dual Acetylcholinesterase (AChE)/Butyrylcholinesterase (BuChE) inhibitors has increased for treating A...

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Detalles Bibliográficos
Autores principales: Zarei, Samaneh, Shafiei, Mohammad, Firouzi, Maryam, Firoozpour, Loghman, Divsalar, Kouros, Asadipour, Ali, Akbarzadeh, Tahmineh, Foroumadi, Alireza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8045006/
https://www.ncbi.nlm.nih.gov/pubmed/33869871
http://dx.doi.org/10.1016/j.heliyon.2021.e06683

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8045006/
https://www.ncbi.nlm.nih.gov/pubmed/33869871
http://dx.doi.org/10.1016/j.heliyon.2021.e06683

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