Early detection of osteoarthritis in the rat with an antibody specific to type II collagen modified by reactive oxygen species

BACKGROUND: Osteoarthritis (OA) is a disease of the whole joint, with articular cartilage breakdown as a major characteristic. Inflammatory mediators, proteases, and oxidants produced by chondrocytes are known to be responsible for driving cartilage degradation. Nevertheless, the early pathogenic ev...

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Detalles Bibliográficos
Autores principales: Gigout, Anne, Harazin, Donata, Topping, Louise M., Merciris, Didier, Lindemann, Sven, Brenneis, Christian, Nissim, Ahuva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8045329/
https://www.ncbi.nlm.nih.gov/pubmed/33853645
http://dx.doi.org/10.1186/s13075-021-02502-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8045329/
https://www.ncbi.nlm.nih.gov/pubmed/33853645
http://dx.doi.org/10.1186/s13075-021-02502-1

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