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Downregulation of metallothionein-2 contributes to oxaliplatin-induced neuropathic pain
BACKGROUND: We previously reported a correlation between small doses of oxaliplatin penetrating onto the spinal cord and acute pain after chemotherapy. Here, we propose that MT2 within the spinal dorsal horns participates in the development of oxaliplatin-induced neuropathic pain and may be a pharma...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8045403/ https://www.ncbi.nlm.nih.gov/pubmed/33849565 http://dx.doi.org/10.1186/s12974-021-02139-6 |