Downregulation of metallothionein-2 contributes to oxaliplatin-induced neuropathic pain

BACKGROUND: We previously reported a correlation between small doses of oxaliplatin penetrating onto the spinal cord and acute pain after chemotherapy. Here, we propose that MT2 within the spinal dorsal horns participates in the development of oxaliplatin-induced neuropathic pain and may be a pharma...

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Detalles Bibliográficos
Autores principales: Huang, Xuelin, Deng, Jie, Xu, Ting, Xin, Wenjun, Zhang, Yuehong, Ruan, Xiangcai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8045403/
https://www.ncbi.nlm.nih.gov/pubmed/33849565
http://dx.doi.org/10.1186/s12974-021-02139-6

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