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Spike is the most recognized antigen in the whole-blood platform in both acute and convalescent COVID-19 patients

OBJECTIVES: To identify the best experimental approach to detect a SARS-CoV-2-specific T cell response using a whole-blood platform. METHODS: Whole-blood from 56 COVID-19 and 23 “NO-COVID-19” individuals were stimulated overnight with different concentrations (0.1 or 1 μg/mL) of SARS-CoV-2 PepTivato...

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Detalles Bibliográficos
Autores principales: Aiello, Alessandra, Najafi Fard, Saeid, Petruccioli, Elisa, Petrone, Linda, Vanini, Valentina, Farroni, Chiara, Cuzzi, Gilda, Navarra, Assunta, Gualano, Gina, Mosti, Silvia, Pierelli, Luca, Nicastri, Emanuele, Goletti, Delia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Author(s). Published by Elsevier Ltd on behalf of International Society for Infectious Diseases. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8045417/
https://www.ncbi.nlm.nih.gov/pubmed/33864921
http://dx.doi.org/10.1016/j.ijid.2021.04.034