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Dodging COVID-19 infection: low expression and localization of ACE2 and TMPRSS2 in multiple donor-derived lines of human umbilical cord-derived mesenchymal stem cells

BACKGROUND: Mesenchymal stem cells derived from human umbilical cord (hUC-MSCs) have immunomodulatory properties that are of interest to treat novel coronavirus disease 2019 (COVID-19). Leng et al. recently reported that hUC-MSCs derived from one donor negatively expressed Angiotensin-Converting Enz...

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Detalles Bibliográficos
Autores principales: Hernandez, Jonathan J., Beaty, Doyle E., Fruhwirth, Logan L., Lopes Chaves, Ana P., Riordan, Neil H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8045575/
https://www.ncbi.nlm.nih.gov/pubmed/33853637
http://dx.doi.org/10.1186/s12967-021-02813-6