Robust modeling of additive and nonadditive variation with intuitive inclusion of expert knowledge

We propose a novel Bayesian approach that robustifies genomic modeling by leveraging expert knowledge (EK) through prior distributions. The central component is the hierarchical decomposition of phenotypic variation into additive and nonadditive genetic variation, which leads to an intuitive model p...

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Detalles Bibliográficos
Autores principales: Hem, Ingeborg Gullikstad, Selle, Maria Lie, Gorjanc, Gregor, Fuglstad, Geir-Arne, Riebler, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Investigation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8045730/
https://www.ncbi.nlm.nih.gov/pubmed/33789346
http://dx.doi.org/10.1093/genetics/iyab002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8045730/
https://www.ncbi.nlm.nih.gov/pubmed/33789346
http://dx.doi.org/10.1093/genetics/iyab002

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