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Robust modeling of additive and nonadditive variation with intuitive inclusion of expert knowledge
We propose a novel Bayesian approach that robustifies genomic modeling by leveraging expert knowledge (EK) through prior distributions. The central component is the hierarchical decomposition of phenotypic variation into additive and nonadditive genetic variation, which leads to an intuitive model p...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8045730/ https://www.ncbi.nlm.nih.gov/pubmed/33789346 http://dx.doi.org/10.1093/genetics/iyab002 |