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Junction plakoglobin regulates and destabilizes HIF2α to inhibit tumorigenesis of renal cell carcinoma

BACKGROUND: Increased hypoxia‐inducible factor 2α (HIF2α) activation is a common event in clear cell renal cell carcinoma (ccRCC) progression. However, the function and underlying mechanism of HIF2α in ccRCC remains uninvestigated. We conducted this study to access the potential link between junctio...

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Detalles Bibliográficos
Autores principales: Chen, Ke, Zeng, Jin, Sun, Yi, Ouyang, Wei, Yu, Gan, Zhou, Hui, Zhang, Yangjun, Yao, Weimin, Xiao, Wei, Hu, Junhui, Xing, Jinchun, Xiao, Kefeng, Wu, Lily, Chen, Zhiqiang, Ye, Zhangqun, Xu, Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8045910/
https://www.ncbi.nlm.nih.gov/pubmed/33591636
http://dx.doi.org/10.1002/cac2.12142